Multi-targeted anti-inflammatory drugs for the treatment of neurological disorders

A Lui, O Alzayat, T Do, D Perekopskiy… - Neural Regeneration …, 2023 - journals.lww.com
Inflammation and kinase pathophysiology in neurological disorders: Inflammation is one of
the common features of various acute and degenerative neurological disorders, such as
stroke, traumatic brain injury (TBI), Alzheimer's disease (AD), Parkinson's disease (PD), and
others. The inflammatory responses are manifested as the synthesis of inflammation
mediators, recruitment of leukocytes, and other secondary injuries. Compelling evidence
shows that a large number of inflammation mediators (eg, thrombin, reactive oxygen …
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