An effective treatment of human diseases using regenerative medicine and cell therapy
approaches requires a large number of cells. Cultivation of cells on microcarriers is a
promising approach due to the high surface‐to‐volume ratios that these microcarriers offer.
Here, multifunctional temperature‐responsive microcarriers (cytoGel) made of an
interpenetrating hydrogel network composed of poly (N‐isopropylacrylamide)(PNIPAM),
poly (ethylene glycol) diacrylate (PEGDA), and gelatin methacryloyl (GelMA) are developed …

In article number 2103192, Mohsen Akbari and co-workers engineer multifunctional
microcarriers for high-throughput cell culture. These microcarriers support cell growth, can
locally deliver biomolecules such as growth factors to the attached cells, and allow for
subsequent cell harvesting via altered environmental temperature. These microcarriers hold
great promise for an industrial-scale culture of therapeutic cells for cell-based therapies and
regenerative medicines.