Multilayered defense in HLA-B51–Associated HIV viral control
YH Zhang, YC Peng, HP Yan, K Xu, M Saito… - The Journal of …, 2011 - journals.aai.org
Polymorphism in the HLA region of a chromosome is the major source of host genetic
variability in HIV-1 outcome, but there is limited understanding of the mechanisms
underlying the beneficial effect of protective class I alleles such as HLA-B57,-B27, and-B51.
Taking advantage of a unique cohort infected with clade B'HIV-1 through contaminated
blood, in which many variables such as the length of infection, the infecting viral strain, and
host genetic background are controlled, we performed a comprehensive study to understand …
variability in HIV-1 outcome, but there is limited understanding of the mechanisms
underlying the beneficial effect of protective class I alleles such as HLA-B57,-B27, and-B51.
Taking advantage of a unique cohort infected with clade B'HIV-1 through contaminated
blood, in which many variables such as the length of infection, the infecting viral strain, and
host genetic background are controlled, we performed a comprehensive study to understand …
Multilayered defense in HLA-B51-associated HIV viral control.
ZYH Zhang YongHong, PYC Peng YanChun… - 2011 - cabidigitallibrary.org
Polymorphism in the HLA region of a chromosome is the major source of host genetic
variability in HIV-1 outcome, but there is limited understanding of the mechanisms
underlying the beneficial effect of protective class I alleles such as HLA-B57,-B27, and-B51.
Taking advantage of a unique cohort infected with clade B′ HIV-1 through contaminated
blood, in which many variables such as the length of infection, the infecting viral strain, and
host genetic background are controlled, we performed a comprehensive study to understand …
variability in HIV-1 outcome, but there is limited understanding of the mechanisms
underlying the beneficial effect of protective class I alleles such as HLA-B57,-B27, and-B51.
Taking advantage of a unique cohort infected with clade B′ HIV-1 through contaminated
blood, in which many variables such as the length of infection, the infecting viral strain, and
host genetic background are controlled, we performed a comprehensive study to understand …
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