Muscarinic receptors—characterization, coupling and function

MP Caulfield - Pharmacology & therapeutics, 1993 - Elsevier
… couple to stimulate phospholipase C, while m2 and m4 muscarinic receptors inhibit … function
of the five muscarinic receptor subtypes. The actions of muscarinic receptors on the heart, …

The molecular basis of muscarinic receptor diversity

TI Bonner - Trends in neurosciences, 1989 - cell.com
… The identity of each of the five receptors as muscarinic receptors has been established by
expression of the clones (see Table I). For the ml receptor this was first done by injecting RNA …

Molecular basis of muscarinic receptor function

J Wess - Trends in pharmacological sciences, 1993 - Elsevier
… features Muscarinic receptors are members of a large family of plasma membrane receptors
… is not only conserved among the muscarinic receptors but also among all other receptors

Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder

P Abrams, KE Andersson, JJ Buccafusco… - British journal of …, 2006 - Wiley Online Library
… This review explores the evolving understanding of muscarinic receptor functions throughout
the body, with particular focus on the bladder, gastrointestinal tract, eye, heart, brain and …

Muscarinic acetylcholine receptors

M Ishii, Y Kurachi - Current pharmaceutical design, 2006 - ingentaconnect.com
… have unraveled the specific function of these muscarinic receptor subtypes, which were not
able to … Based on these findings, muscarinic receptors have been emerging as an important …

Therapeutic opportunities for muscarinic receptors in the central nervous system

CC Felder, FP Bymaster, J Ward… - Journal of medicinal …, 2000 - ACS Publications
… of the muscarinic receptor family and therapeutic opportunities for muscarinic intervention
in … of muscarinic receptors will be followed by summaries of the involvement of this family of …

Therapeutic opportunities from muscarinic receptor research

RM Eglen, A Choppin, N Watson - Trends in pharmacological sciences, 2001 - cell.com
… in urinary incontinence is the nonselective muscarinic receptor antagonist tolterodine. This
… or M 5 receptors. In this article, the current status of muscarinic receptor research is critically …

Muscarinic receptor subtypes in airways

PJ Barnes - Life sciences, 1993 - Elsevier
… studies indicate that these receptors are localized to the … not appear to have these parenchymal
muscarinic receptors (3,4)… that these muscarinic receptors are of the ml-receptor subclass …

Pirenzepine distinguishes between different subclasses of muscarinic receptors

R Hammer, CP Berrie, NJM Birdsall, ASV Burgen… - Nature, 1980 - nature.com
… pirenzepine to muscarinic receptors in homogenates of several peripheral tissues and in
different regions of the rat brain has been compared to that of a classical muscarinic antagonist, …

[图书][B] Muscarinic receptors

AD Fryer, A Christopoulos, NM Nathanson - 2012 - books.google.com
muscarinic receptor subtypes provided the opportunity to develop drugs that would target
discrete subsets of muscarinic receptors … and negatively on the receptors at sites distinct from …