CA Ascoli - Nature biotechnology, 2021 - nature.com
… of SARS-CoV-2 viral proteins in biofluids (mainly lysates from … ‘Escape variant’ detection is among the several well … polyclonalantibodies to N protein to detect SARS-CoV-2. Even …
… immuneescape strategies of SARS-CoV-2, primarily innate … The SARS-CoV-2infection causes the production dysregulation … the virus by polyclonal human plasma antibodies. However, …
… viral variants with mutations that reduce neutralization by polyclonalantibodies elicited by vaccination or infection. … by largely distinct sets of mutations: LY-CoV016 is most strongly …
… activity of polyclonalantibodyresponse to SARS-CoV-2infection is due to antibodies that … functional effects of RBD mutations to largely predict which escapemutations will arise when …
… neutralization by polyclonalantibodies of the kind SARS-CoV-2 encounters in infections, with … This lineage has spread widely in Europe and is reported to have originated in Spain 52 . …
D Focosi, F Maggi - Reviews in medical virology, 2021 - Wiley Online Library
… than 400,000 full SARS-CoV-2 proteome sequences (mostly from … that Spike protein mutations in novel SARS-CoV-2 ‘variants of … DMS was also applied to polyclonalantibodies in CCP. …
… We use deep mutational scanning to show that mutations to the … variant infection elicits a polyclonalantibodyresponse most … , we mapped antibody-binding escapemutations using the …
… by these antibodies is notably less affected by mutations at … affect which mutations are identified as antibody-escape variants. … essentially as described in [70], using a codon-optimized …
… specific mainly to the spike glycoprotein, all of its parts … of antibody mixtures with non-overlapping escapemutations should help … Polyclonal sera also contain non-neutralizing antibodies …