… (eg Vero cells) support SARS-CoV-2 entry mainly by endocytosis, … and still remain viable and
infectious, as shown in African … receptor-binding domain (RBD) upon evolution of mutations …

… future mutations, for example, allowing mutations that escape … shifts in mutational effects on
ACE2 binding are primarily … S6, C to E) (15, 18) and reduce neutralization by polyclonal sera (…

… escape mutation map not only confirms the widely circulating … patients infected with
early-circulating SARS-CoV-2 strains … sites on the RBD targeted by polyclonal antibodies (Fig. 6a, …

… We find that although neutralization is largely preserved … Since the first described case of
SARS-CoV-2 infection in … , we identified consensus sequence mutations that represent the …

… characterization of spike mutations are mainly based on the use … also act as an immune
escape mutation conferring reduced … the treatment of individuals infected with SARS-CoV-2 (11), …

… ability of SARS-CoV-2 to acquire mutations has resulted in … on diminished taste upon
SARS-CoV-2 infection [46]. The … antiviral agents have been widely administered as preventive …

… recently had SARS-CoV-2 infections. The strongest serum … how mutations in spike affect
neutralization by the polyclonal … non-RBD serum escape mutations act primarily by shifting the …

… of Omicron RBD mutations on polyclonal antibody responses and … The Beta and Delta variant
mutations primarily reside at sites … Mapping mutations to the SARS-CoV-2 RBD that escape …

… of Fabs in complex with the SARS-CoV-2 RBD at 3.2 and 3.0 Å … that the two complexes
were essentially identical (RMSD = … can be used to counter SARS-CoV-2 infections either as a …

… endowed by antibodies targeting SARS-CoV-2 spike protein … of spike, polyclonal immunity
to SARS-CoV-2 spike, and the … , or in cases of breakthrough infection. At the same time, …