Myo-inositol Oxygenase Overexpression Rescues Vitamin C Deficient Arabidopsis (vtc) Mutants
M Acosta-Gamboa Lucia, N Nirman, MJ Karina… - bioRxiv, 2021 - biorxiv.org
Biosynthesis of l-ascorbate (AsA) in plants is carried out by a complex metabolic network,
which involves d-mannose/l-galactose, d-galacturonate, l-gulose, and myo-inositol as main
precursors. Arabidopsis lines over-expressing enzymes in the myo-inositol pathway have
elevated AsA, accumulate more biomass of both aerial and root tissues, and are tolerant to
abiotic stresses as shown by manual and digital phenotyping. We crossed myo-inositol
oxygenase (MIOX4) over-expressers with two low-vitamin C mutants (vtc 1-1 and vtc 2-1) …
which involves d-mannose/l-galactose, d-galacturonate, l-gulose, and myo-inositol as main
precursors. Arabidopsis lines over-expressing enzymes in the myo-inositol pathway have
elevated AsA, accumulate more biomass of both aerial and root tissues, and are tolerant to
abiotic stresses as shown by manual and digital phenotyping. We crossed myo-inositol
oxygenase (MIOX4) over-expressers with two low-vitamin C mutants (vtc 1-1 and vtc 2-1) …
Myo-inositol Oxygenase Overexpression Rescues Vitamin C Deficient Arabidopsis (vtc) Mutants
Biosynthesis of l-ascorbate (AsA) in plants is carried out by a complex metabolic network,
which involves d-mannose/l-galactose, d-galacturonate, l-gulose, and myo-inositol as main
precursors. Arabidopsis lines over-expressing enzymes in the myo-inositol pathway have
elevated AsA, accumulate more biomass of both aerial and root tissues, and are tolerant to
abiotic stresses as shown by manual and digital phenotyping. We crossed myo-inositol
oxygenase (MIOX4) over-expressers with two low-vitamin C mutants (vtc 1-1 and vtc 2-1) …
which involves d-mannose/l-galactose, d-galacturonate, l-gulose, and myo-inositol as main
precursors. Arabidopsis lines over-expressing enzymes in the myo-inositol pathway have
elevated AsA, accumulate more biomass of both aerial and root tissues, and are tolerant to
abiotic stresses as shown by manual and digital phenotyping. We crossed myo-inositol
oxygenase (MIOX4) over-expressers with two low-vitamin C mutants (vtc 1-1 and vtc 2-1) …