Myocardial ischemia-reperfusion injury and the influence of inflammation

M Algoet, S Janssens, U Himmelreich, W Gsell… - Trends in cardiovascular …, 2023 - Elsevier
Acute myocardial infarction is caused by a sudden coronary artery occlusion and leads to
ischemia in the corresponding myocardial territory which generally results in myocardial
necrosis. Without restoration of coronary perfusion, myocardial scar formation will cause
adverse remodelling of the myocardium and heart failure. Successful introduction of
percutaneous coronary intervention and surgical coronary artery bypass grafting made it
possible to achieve early revascularisation/reperfusion, hence limiting the ischemic zone of …
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