Myosin Heavy Chain Myopathy and Immune-Mediated Muscular Disorders
SA Durward-Akhurst… - … Clinics: Equine Practice, 2025 - vetequine.theclinics.com
Inflammatory myopathies are a heterogenous group of muscle disorders characterized by
infiltration of leukocytes into skeletal muscle and around blood vessels. 1–3 Neutrophils,
eosinophils, or lymphocytes predominate depending on the inciting cause, which is in stark
contrast to most exertional myopathies that have macrophage infiltration of myofibers. 4, 5
Inflammatory myopathies are less well characterized than in other species, with extensive
overlap between myopathies with apparent infectious and immune-mediated components …
infiltration of leukocytes into skeletal muscle and around blood vessels. 1–3 Neutrophils,
eosinophils, or lymphocytes predominate depending on the inciting cause, which is in stark
contrast to most exertional myopathies that have macrophage infiltration of myofibers. 4, 5
Inflammatory myopathies are less well characterized than in other species, with extensive
overlap between myopathies with apparent infectious and immune-mediated components …
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