NOD-like receptors and the innate immune system: coping with danger, damage and death
K Kersse, MJM Bertrand, M Lamkanfi… - Cytokine & growth factor …, 2011 - Elsevier
Members of the family of NOD-like receptors (NLRs) play essential roles in innate immunity
by detecting intracellular 'pathogen-associated molecular patterns'(PAMPs) and 'danger-
associated molecular patterns'(DAMPs). These molecules reveal the presence of
pathogenic infection, abiotic stress, environmental insults, cellular damage, and cell death.
NLR family members can be divided in two functional groups. One group consists of
intracellular receptors, such as NLRP1, NLRP3, NLRP6 and NLRC4, which mediate the …
by detecting intracellular 'pathogen-associated molecular patterns'(PAMPs) and 'danger-
associated molecular patterns'(DAMPs). These molecules reveal the presence of
pathogenic infection, abiotic stress, environmental insults, cellular damage, and cell death.
NLR family members can be divided in two functional groups. One group consists of
intracellular receptors, such as NLRP1, NLRP3, NLRP6 and NLRC4, which mediate the …
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