Supercritical antisolvent micronization (SAS) has been used to obtain microparticles of
several kind of materials, but the production of nanoparticles have been observed and
studied in some cases only. This work is focused on the systematic production of
nanoparticles using SAS. We performed experiments on several compounds and different
solvents at selected operating conditions, obtaining nanoparticles with mean diameters
ranging between 45 and 150nm, thus demonstrating that nanoparticles production is a …