Natural killer cells are characterized by the concomitantly increased interferon-γ and cytotoxicity in acute resolved hepatitis B patients
Natural killer (NK) cells are abundant in the liver and have been implicated in inducing
hepatocellular damage in patients with chronic hepatitis B virus (HBV) infection. However,
the role of NK cells in acute HBV infection remains to be elucidated. We comprehensively
characterized NK cells and investigated their roles in HBV clearance and liver pathology in
19 chronic hepatitis B (CHB) patients and 21 acute hepatitis B (AHB) patients as well as 16
healthy subjects. It was found that NKp46+ NK cells were enriched in the livers of AHB and …
hepatocellular damage in patients with chronic hepatitis B virus (HBV) infection. However,
the role of NK cells in acute HBV infection remains to be elucidated. We comprehensively
characterized NK cells and investigated their roles in HBV clearance and liver pathology in
19 chronic hepatitis B (CHB) patients and 21 acute hepatitis B (AHB) patients as well as 16
healthy subjects. It was found that NKp46+ NK cells were enriched in the livers of AHB and …
Natural killer cells are characterized by the concomitantly increased interferon-γ and cytotoxicity in acute resolved hepatitis B patients.
ZJJ Zhao JuanJuan, LYG Li YongGang, JL Jin Lei… - 2012 - cabidigitallibrary.org
Natural killer (NK) cells are abundant in the liver and have been implicated in inducing
hepatocellular damage in patients with chronic hepatitis B virus (HBV) infection. However,
the role of NK cells in acute HBV infection remains to be elucidated. We comprehensively
characterized NK cells and investigated their roles in HBV clearance and liver pathology in
19 chronic hepatitis B (CHB) patients and 21 acute hepatitis B (AHB) patients as well as 16
healthy subjects. It was found that NKp46+ NK cells were enriched in the livers of AHB and …
hepatocellular damage in patients with chronic hepatitis B virus (HBV) infection. However,
the role of NK cells in acute HBV infection remains to be elucidated. We comprehensively
characterized NK cells and investigated their roles in HBV clearance and liver pathology in
19 chronic hepatitis B (CHB) patients and 21 acute hepatitis B (AHB) patients as well as 16
healthy subjects. It was found that NKp46+ NK cells were enriched in the livers of AHB and …
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