Nerve repair scaffolds having high microchannel volume and methods for making the same

JS Sakamoto, D Shahriari, MH Tuszynski… - US Patent …, 2019 - Google Patents
Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a
sheath. Each microchannel comprises a porous wall having a thickness of≤ about 100 μm
that is formed from a biocompatible and biodegradable material comprising a polyester
polymer. The polyester polymer may be polycaprolactone, poly (lactic-co-glycolic acid)
polymer, and combinations thereof. The tissue scaffolds have high open volume% enabling
superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near …

Nerve repair scaffolds having high microchannel volume and methods for making the same

JS Sakamoto, D Shahriari, MH Tuszynski… - US Patent …, 2021 - Google Patents
Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a
sheath. Each microchannel comprises a porous wall having a thickness of≤ about 100 μm
that is formed from a biocompatible and biodegradable material comprising a polyester
polymer. The polyester polymer may be polycaprolactone, poly (lactic-co-glycolic acid)
polymer, and combinations thereof. The tissue scaffolds have high open volume% enabling
superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near …
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