Neural progenitors proliferation is inhibited by EphB3 in the developing subventricular zone

K del Valle, MH Theus, JR Bethea, DJ Liebl… - International journal of …, 2011 - Elsevier
The subventricular zone (SVZ) of the mammalian forebrain is a major source of multipotent
stem cells during development, and contributes to neurogenesis throughout the lifespan of
the organism. Several studies described molecules regulating adult neurogenesis, however,
few of them have examined neurogenesis in the early postnatal period. Adult neurogenesis
is regulated in part by ephrinB3 and its receptors, so we examined the role of EphB3 on
neural stem/progenitor cell (NSPC) proliferation in early postnatal development in the SVZ …
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