Neurologic features of immunoglobulin G4–related disease
M AbdelRazek, JH Stone - Rheumatic Disease Clinics, 2017 - rheumatic.theclinics.com
Immunoglobulin (Ig) G4–related disease (IgG4-RD) has been recognized as a discrete,
multiorgan condition only since 2003. 1 This immune-mediated disease can affect both the
central and peripheral nervous systems, as well as nearly any other organ in the body. The
most common neurologic features of IgG4-RD result from disease in the (1) orbits;(2)
pachymeninges, including complications of pachymeningeal inflammation within the orbital
apex and cavernous sinus; and (3) substance of the pituitary gland and stalk, leading to …
multiorgan condition only since 2003. 1 This immune-mediated disease can affect both the
central and peripheral nervous systems, as well as nearly any other organ in the body. The
most common neurologic features of IgG4-RD result from disease in the (1) orbits;(2)
pachymeninges, including complications of pachymeningeal inflammation within the orbital
apex and cavernous sinus; and (3) substance of the pituitary gland and stalk, leading to …
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