New thiophene-derived α-aminophosphonic acids: Synthesis under microwave irradiations, antioxidant and antifungal activities, DFT investigations and SARS-CoV-2 …

H Tlidjane, N Chafai, S Chafaa, C Bensouici… - Journal of Molecular …, 2022 - Elsevier
Four new α-aminophosphonic acids containing thiophene ring have been synthesized using
simple, neat and catalyst-free conditions, more convenient and eco-friendly method under
microwave irradiations. The structures of the title molecules have been confirmed by UV-Vis,
FT-IR, 1 H NMR, 13 C NMR and 31 P NMR. Moreover, their antioxidant activity was
evaluated using DPPH, ABTS and phenantroline methods; the obtained results indicate that
the title molecules exhibit excellent activity better than standards BHT and BHA. Also, the …
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