The accurate genetic screening of pre-implantation embryos currently entails the use of
technically challenging and biologically invasive biopsies of the human embryos.
Investigating a more conservative sampling approach has emerged as a timely and desired
alternative. Circulating cell-free embryonic DNA is present in the blastocoel fluid and spent
culture media of blastocysts, and this has lately been sought as an attractive source of
genetic information. The genetic analysis of cell-free embryonic DNA has been reported, to …

The authors of the above article would like to apologise for an error in the 'Clinical studies'
section of 'BF sampling'. The article originally reported that the median volume of blastocoel
fluid (BF) collected by Palini et al.(2013) was 4 μl. The actual volume collected by Palini et
al. was 0.3–0.5 nl expelled into 4 μl of 1 mmol/l Tris-HCl and 0.1 mmol/l EDTA (pH 8.0).