Gliomas are primary brain tumors of central nervous system. Appropriate resection of
gliomas in the early tumor stage is known to increase survival rate. However, the accurate
resection of tumor is a challenging problem because the soft tissue shift may occur during
the operation. To provide proper guidance to neurosurgery, it is necessary to align magnetic
resonance imaging (MRI) and intra-operative ultrasound (iUS). In previous studies, many
algorithms tried to find fiducial points that can lead to the appropriate registration. But these …