gliomas in the early tumor stage is known to increase survival rate. However, the accurate
resection of tumor is a challenging problem because the soft tissue shift may occur during
the operation. To provide proper guidance to neurosurgery, it is necessary to align magnetic
resonance imaging (MRI) and intra-operative ultrasound (iUS). In previous studies, many
algorithms tried to find fiducial points that can lead to the appropriate registration. But these …