Non-rapid eye movement sleep and wake neurophysiology in schizophrenia

N Kozhemiako, J Wang, C Jiang, LA Wang, G Gai… - Elife, 2022 - elifesciences.org
Motivated by the potential of objective neurophysiological markers to index thalamocortical
function in patients with severe psychiatric illnesses, we comprehensively characterized key
non-rapid eye movement (NREM) sleep parameters across multiple domains, their
interdependencies, and their relationship to waking event-related potentials and symptom
severity. In 72 schizophrenia (SCZ) patients and 58 controls, we confirmed a marked
reduction in sleep spindle density in SCZ and extended these findings to show that fast and …

Non-rapid eye movement sleep and wake neurophysiology in schizophrenia

K Nataliia, J Wang, C Jiang, LA Wang, G Guanchen… - eLife, 2022 - search.proquest.com
Motivated by the potential of objective neurophysiological markers to index thalamocortical
function in patients with severe psychiatric illnesses, we comprehensively characterized key
non-rapid eye movement (NREM) sleep parameters across multiple domains, their
interdependencies, and their relationship to waking event-related potentials and symptom
severity. In 72 schizophrenia (SCZ) patients and 58 controls, we confirmed a marked
reduction in sleep spindle density in SCZ and extended these findings to show that fast and …
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