the pressure (MPa), temperature (° C) and process time (min) on the inactivation of
Lactobacillus casei cells inoculated in apple juice (10 7 CFU/mL). The effects of process
variables on the logarithmic reduction of L. casei cell counts were estimated by a two-level
Plackett–Burman factorial design. A Box–Behnken design was subsequently employed to
evaluate the interaction between the different factors on the supercritical microbial …