… gene delivery by learning from the attributes which viruses have evolved; attributes that enable
translocation of viral … barriers to gene transfer discussed above relate to access of DNA to …

… viruses and related toxicity make non-viral gene delivery systems the vector of choice in gene
therapy. … In spite of these developments, overcoming the above-discussed cellular barriers …

… viral gene transfer vehicle is the phenomenon known as insertional mutagenesis ie ectopic
chromosomal integration of viral DNA … Lipid nano emulsion is considered to be superior to …

… barrier mentioned above and … with viruses, non-viral vectors continue to attract a great deal
of interest due to their advantageous safety profile. Add to the safety issues outlined above, …

… Gene vectors generally include viral vectors and non-viral vectors. Presently, approximately
70% of clinical gene therapy trials employ viral … effective non-viral vectors, show superior …

… Viral vectors such as attenuated viruses, adenoviruses and retroviruses, have thus far proven
to have significantly … Although non‐viral vectors are considered superior vehicles for gene …

… of gene therapy development, non-viral gene therapies were considered clinically unfeasible
due to their poor gene delivery efficiency compared to viral delivery … non-viral gene delivery …

… both viral and non-viral vectors are used as delivery systems … for superior performance with
enhanced gene stability, high … various non-viral vector-mediated gene therapy approaches …

… and safe, numerous gene transfer systems or gene vectors have been … , viral gene delivery
and non-viral gene delivery, depending on the involvement of vectors. Both viral and non-viral …

… viral vectors and non-viral vectors have been used as gene carriers for effective and safe
gene delivery… to 40 kbp have shown a superior performance when transfected with this vector, …