Nonconvective forces: a critical and often ignored component in the echocardiographic assessment of transvalvular pressure gradients

MS Firstenberg, EE Abel, TJ Papadimos… - Cardiology research …, 2012 - Wiley Online Library
MS Firstenberg, EE Abel, TJ Papadimos, RS Tripathi
Cardiology research and practice, 2012Wiley Online Library
Echocardiography is routinely used to assess ventricular and valvular function, particularly
in patients with known or suspected cardiac disease and who have evidence of
hemodynamic compromise. A cornerstone to the use of echocardiographic imaging is not
only the qualitative assessment, but also the quantitative Doppler‐derived velocity
characteristics of intracardiac blood flow. While simplified equations, such as the modified
Bernoulli equation, are used to estimate intracardiac pressure gradients based upon …
Echocardiography is routinely used to assess ventricular and valvular function, particularly in patients with known or suspected cardiac disease and who have evidence of hemodynamic compromise. A cornerstone to the use of echocardiographic imaging is not only the qualitative assessment, but also the quantitative Doppler‐derived velocity characteristics of intracardiac blood flow. While simplified equations, such as the modified Bernoulli equation, are used to estimate intracardiac pressure gradients based upon Doppler velocity data, these modified equations are based upon assumptions of the varying contributions of the different forces that contribute to blood flow. Unfortunately, the assumptions can result in significant miscalculations in determining a gradient if not completely understood or they are misapplied. We briefly summarize the principles of fluid dynamics that are used clinically with some of the inherent limitations of routine broad application of the simplified Bernoulli equation.
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