Noninvasive biomarkers in monitoring kidney allograft health
JM O'Callaghan, SR Knight - Current Opinion in Organ …, 2019 - journals.lww.com
Current Opinion in Organ Transplantation, 2019•journals.lww.com
Noninvasive, rapid, and accurate tests for risk-prediction and diagnosis in renal transplant
allografts are urgently required. The ideal candidate is one that can be measured in either
urine or blood, is cheap, and is both sensitive and specific for the condition of interest.
Numerous strategies have been proposed, with varying degrees of clinical and preclinical
success. A few that meet the essential criteria have been evaluated; a few have made it as
far as clinical testing.
allografts are urgently required. The ideal candidate is one that can be measured in either
urine or blood, is cheap, and is both sensitive and specific for the condition of interest.
Numerous strategies have been proposed, with varying degrees of clinical and preclinical
success. A few that meet the essential criteria have been evaluated; a few have made it as
far as clinical testing.
Summary
Noninvasive, rapid, and accurate tests for risk-prediction and diagnosis in renal transplant allografts are urgently required. The ideal candidate is one that can be measured in either urine or blood, is cheap, and is both sensitive and specific for the condition of interest. Numerous strategies have been proposed, with varying degrees of clinical and preclinical success. A few that meet the essential criteria have been evaluated; a few have made it as far as clinical testing.
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