Normal milk microbiome is reestablished following experimental infection with Escherichia coli independent of intramammary antibiotic treatment with a third …
Background The use of antimicrobials in food animals and the emergence of antimicrobial
resistance are global concerns. Ceftiofur is the only third-generation cephalosporin labeled
for veterinary use in the USA, and it is the drug of choice in the majority of dairy farms for the
treatment of mastitis. Here, we use next-generation sequencing to describe longitudinal
changes that occur in the milk microbiome before, during, and after infection and treatment
with ceftiofur. Twelve animals were intramammary challenged with Escherichia coli in one …
resistance are global concerns. Ceftiofur is the only third-generation cephalosporin labeled
for veterinary use in the USA, and it is the drug of choice in the majority of dairy farms for the
treatment of mastitis. Here, we use next-generation sequencing to describe longitudinal
changes that occur in the milk microbiome before, during, and after infection and treatment
with ceftiofur. Twelve animals were intramammary challenged with Escherichia coli in one …
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