Novel VIM metallo-β-lactamase variant, VIM-24, from a Klebsiella pneumoniae isolate from Colombia
Antimicrobial agents and chemotherapy, 2011•Am Soc Microbiol
We report the emergence of a novel VIM variant (VIM-24) in a Klebsiella pneumoniae isolate
in Colombia. The isolate displays MICs for carbapenems below the resistance breakpoints,
posing a real challenge for its detection. The bla VIM-24 gene was located within a class 1
integron carried on a large plasmid. Further studies are needed to clarify its epidemiological
and clinical impact.
in Colombia. The isolate displays MICs for carbapenems below the resistance breakpoints,
posing a real challenge for its detection. The bla VIM-24 gene was located within a class 1
integron carried on a large plasmid. Further studies are needed to clarify its epidemiological
and clinical impact.
Abstract
We report the emergence of a novel VIM variant (VIM-24) in a Klebsiella pneumoniae isolate in Colombia. The isolate displays MICs for carbapenems below the resistance breakpoints, posing a real challenge for its detection. The blaVIM-24 gene was located within a class 1 integron carried on a large plasmid. Further studies are needed to clarify its epidemiological and clinical impact.
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