Novel method suggests global superiority of short-duration antibiotics for intra-abdominal infections
AR Celestin, SR Odom, K Angelidou… - Clinical Infectious …, 2017 - academic.oup.com
AR Celestin, SR Odom, K Angelidou, SR Evans, R Coimbra, CA Guidry, J Cuschieri…
Clinical Infectious Diseases, 2017•academic.oup.comDesirability of outcome ranking and response adjusted for duration of antibiotic risk
(DOOR/RADAR) are novel and innovative methods of evaluating data in antibiotic trials. We
analyzed data from a noninferiority trial of short-course antimicrobial therapy for intra-
abdominal infection (STOP-IT), and results suggest global superiority of short-duration
therapy for intra-abdominal infections.
(DOOR/RADAR) are novel and innovative methods of evaluating data in antibiotic trials. We
analyzed data from a noninferiority trial of short-course antimicrobial therapy for intra-
abdominal infection (STOP-IT), and results suggest global superiority of short-duration
therapy for intra-abdominal infections.
Abstract
Desirability of outcome ranking and response adjusted for duration of antibiotic risk (DOOR/RADAR) are novel and innovative methods of evaluating data in antibiotic trials. We analyzed data from a noninferiority trial of short-course antimicrobial therapy for intra-abdominal infection (STOP-IT), and results suggest global superiority of short-duration therapy for intra-abdominal infections.
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