[HTML][HTML] Novel method to characterize primary cultures of leiomyoma and myometrium with the use of confirmatory biomarker gene arrays
M Malik, WH Catherino - Fertility and sterility, 2007 - Elsevier
OBJECTIVE: To develop a rapid biomarker method for confirming that leiomyoma and
myometrium primary cultures maintain the molecular phenotype of the progenitor tissues.
DESIGN: Confirmation of primary cultures from leiomyoma and myometrium tissues.
SETTING: University hospital. PATIENT (S): Women undergoing hysterectomy for
symptomatic leiomyomas. INTERVENTION (S): Primary cell cultures, reverse-transcriptase
polymerase chain reaction (RT-PCR), microarray, real time RT-PCR, and …
myometrium primary cultures maintain the molecular phenotype of the progenitor tissues.
DESIGN: Confirmation of primary cultures from leiomyoma and myometrium tissues.
SETTING: University hospital. PATIENT (S): Women undergoing hysterectomy for
symptomatic leiomyomas. INTERVENTION (S): Primary cell cultures, reverse-transcriptase
polymerase chain reaction (RT-PCR), microarray, real time RT-PCR, and …
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