Highlights•Cyclodextrins can form non covalent inclusion complexes by molecular
encapsulation.•Thermodynamic parameters account for a spontaneous and exothermic
inclusion process.•Isotherms shape confirms the displacement of cyclodextrin water
molecules by the ligand.•Cyclodextrins allow enhancing solubility and stability of a wide
range of compounds.•They are widely used in many pharmaceutical and food industrial
products.Cyclodextrins (CDs) are cyclic oligosaccharides composed of linked …

Cyclodextrins (CDs) are cyclic oligosaccharides composed of linked glucopyranose
subunits. The main property of CDs is that their hydrophobic inner cavity forms inclusion
complexes with a wide range of guest molecules, while the hydrophilic exterior enhances
CD solubility in water. Because of their molecular inclusion capability, the properties of the
materials with which they complex can be significantly modified. Particularly, solubility and
stability of bioactive compounds to be used as nutraceuticals, could be improved by …