… The nucleus has a direct relation not only to the extracellular … Therefore, cardiomyocyte
nuclei are not only capable of … be found in cardiomyocyte nuclei during pathological processes …

… The Myocardin-related transcription factor-A (MRTF-A) pathway is also affected in Lmna
mutant mice, with reduced accumulation of MRTF-A in cardiomyocyte nuclei, and reduced …

… While mechanosensing at the plasma membrane and the … It is clear that cardiac myocyte
nuclei undergo substantial … extent to which the nucleus itself can act as a mechanosensor. …

… of cardiomyocytes, but also cardiomyocyte electrophysiology. Matrix stiffness, geometry,
and topography thus combine as inputs to inform cardiomyocyte differentiation and maturation. …

… and adapted to measure cardiomyocyte receptor-ligand … about cardiomyocyte mechanobiology.
Here, we take stock at the different tools for exploring cardiomyocyte mechanosensing …

… can lead to cardiac myocyte hypertrophy, cellular growth that … the primary mechanosensor
in cardiac myocytes have been … mechanosensitive mechanisms in the nucleus. New and …

… of the nucleus as a mechanosensor and the … -nucleus connections, microtubules and desmin
intermediate filaments were shown to control nuclear shape and integrity in cardiomyocytes…

… shown to connect the Z-disc to the cardiomyocyte nucleus [25, 26], while other proteins like
… believed to be involved in ECM-based mechanosensing since it plays a crucial role in adult …

… components can sense mechanical load during cardiomyocyte contraction and, in
particular, whether αT-catenin can function as a mechanosensor while interacting with Pkp2. …

… effects of mechanosensing events at cell–matrix adhesions, MRTFA is released and subsequently
enters the nucleus to … Cardiomyocytes perceive substrate rigidity through a multimodal …