Nutrient regulation: conjugated linoleic acid's inflammatory and browning properties in adipose tissue
W Shen, MK McIntosh - Annual Review of Nutrition, 2016 - annualreviews.org
Obesity is the most widespread nutritional disease in the United States. Developing effective
and safe strategies to manage excess body weight is therefore of paramount importance.
One potential strategy to reduce obesity is to consume conjugated linoleic acid (CLA)
supplements containing isomers cis-9, trans-11 and trans-10, cis-12, or trans-10, cis-12
alone. Proposed antiobesity mechanisms of CLA include regulation of (a) adipogenesis,(b)
lipid metabolism,(c) inflammation,(d) adipocyte apoptosis,(e) browning or beiging of adipose …
and safe strategies to manage excess body weight is therefore of paramount importance.
One potential strategy to reduce obesity is to consume conjugated linoleic acid (CLA)
supplements containing isomers cis-9, trans-11 and trans-10, cis-12, or trans-10, cis-12
alone. Proposed antiobesity mechanisms of CLA include regulation of (a) adipogenesis,(b)
lipid metabolism,(c) inflammation,(d) adipocyte apoptosis,(e) browning or beiging of adipose …
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