Pharmacology of oleanolic acid and ursolic acid

J Liu - Journal of ethnopharmacology, 1995 - Elsevier
… Both oleanolic acid and ursolic acid are effective in protecting against chemically induced
liver injury in laboratory animals. Oleanolic acid has been marketed in China as an oral drug …

Antiviral activities of oleanolic acid and its analogues

V Khwaza, OO Oyedeji, BA Aderibigbe - Molecules, 2018 - mdpi.com
… This article reports a review of the analogues of oleanolic acid and their selected pathogenic
… In this study we review modifications of the basic oleanolic acid structure that have been …

Oleanolic acid and ursolic acid: research perspectives

J Liu - Journal of ethnopharmacology, 2005 - Elsevier
… A major advancement during the past 10 years is the synthesis of derivatives from the
natural triterpenoids such as oleanolic acid. For example, the oleanolic acid derivative 2-cyano-3,…

Oleanolic acid increases plasma ANP levels via an accentuation of cardiac ANP synthesis and secretion in rats

HY Kim, KW Cho, DG Kang, HS Lee - European journal of pharmacology, 2013 - Elsevier
… The present study was designed to identify the effects of oleanolic acid on plasma levels and
oleanolic acid increased plasma ANP levels in a dose-related manner. Similarly, oleanolic

Oleanolic acid alters multiple cell signaling pathways: implication in cancer prevention and therapy

L Žiberna, D Šamec, A Mocan, SF Nabavi… - International journal of …, 2017 - mdpi.com
… Main molecular mechanisms underlying anticancer effects of oleanolic acid are mediated …
In this work, we critically review the scientific literature on the molecular targets of oleanolic

Oleanolic acid-an &alpha-Glucosidase inhibitory and antihyperglycemic active compound from the fruits of Sonneratia caseolaris

AK Tiwari, V Viswanadh, PM Gowri, AZ Ali… - Open Access Journal …, 2010 - epubs.icar.org.in
… whether presence of oleanolic acid in diet has any glycemic importance, we incubated
oleanolic acid invitro with substrate p-NPG for the first five minutes and then added crude α-…

Anti-inflammatory activity of oleanolic acid by inhibition of secretory phospholipase A2

KK Dharmappa, RV Kumar, A Nataraju… - Planta …, 2009 - thieme-connect.com
… effect of oleanolic acid on sPLA 2 , a key enzyme in inflammatory reactions. Oleanolic acid
… Alpha-lipoic acid an inhibitor of secretory phospholipase A 2 with anti-inflammatory activity. …

Synthesis, Anti‐Oomycete and Anti‐Fungal Activities of Anhydride Derivatives of Oleanolic Acid

Z Che, R Wang, Y Li, W Yin, H Sun, S Xu… - Chemistry & … - Wiley Online Library
… of oleanolic acid. 3) Proving the importance of introducing an active acyloxy group at the C-28
carboxyl position of oleanolic … , and development of oleanolic acid derivatives as potential …

Anti‐complement activity of oleanolic acid: an inhibitor of C3‐convertase of the classical complement pathway

A Kapil, S Sharma - Journal of pharmacy and pharmacology, 1994 - Wiley Online Library
Abstract— Oleanolic acid is a naturally occurring compound, isolated from Luffa cylindrica, …
of oleanolic acid showed constant inhibitory effects on immunohaemolysis. Oleanolic acid …

Inhibitory effect of oleanolic acid on 12-O-tetradecanoylphorbol-13-acetate-induced gene expression in mouse skin

T Oguro, J Liu, CD Klaassen, T Yoshida - Toxicological Sciences, 1998 - Elsevier
Oleanolic acid (OA) has been shown to inhibit mouse skin tumor promotion by 12-O-…
Protective effect of oleanolic acid and ursolic acid against lipid peroxidation Biochem. Int. 24…