Omega-3 polyunsaturated fatty acids in treating non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled trial
Background & aims: Few clinical trials have addressed the potential benefits of omega-3
polyunsaturated fatty acids (PUFAs) on non-alcoholic steatohepatitis (NASH). We evaluated
the effects of supplementation with omega-3 PUFAs from flaxseed and fish oils in patients
with biopsy-proven NASH. Methods Patients received three capsules daily, each containing
0.315 g of omega-3 PUFAs (64% alpha-linolenic [ALA], 16% eicosapentaenoic [EPA], and
21% docosahexaenoic [DHA] acids; n-3 group, n= 27) or mineral oil (placebo group, n= 23) …
polyunsaturated fatty acids (PUFAs) on non-alcoholic steatohepatitis (NASH). We evaluated
the effects of supplementation with omega-3 PUFAs from flaxseed and fish oils in patients
with biopsy-proven NASH. Methods Patients received three capsules daily, each containing
0.315 g of omega-3 PUFAs (64% alpha-linolenic [ALA], 16% eicosapentaenoic [EPA], and
21% docosahexaenoic [DHA] acids; n-3 group, n= 27) or mineral oil (placebo group, n= 23) …
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