Working in a research group, integrating all the researchers can be the main factor for success in producing quality scientific research. In this sense, this paper presents a case study of the application of Scrum, an agile methodology for software development management, in the context of research-oriented projects. A group of undergraduate of the Computer Science course, master and doctoral students of the Informatics Post-graduation Program from the Federal University of Amazonas participated of the study. The Scrum controlled the whole research process, from initial literature review, through the software development phase, to the writing and presentation of the final project or thesis. During the study, the methodology was adapted to the context of research, seeking to resolve issues affecting the progress of the scientific production. At the end of every Sprint, the team held a meeting to validate the Scrum artifacts, exchange experiences and hold a debate on what the team produced during the Sprint. Observation and opinion survey show that the results were satisfactory, showing development in the production and quality of scientific work. This paper presents suggestions for improvements in the use of the Scrum methodology in research groups.