One-pot synthesis of coumarine derivatives using butylenebispyridinium hydrogen sulfate as novel ionic liquid catalyst

S Rezayati, F Sheikholeslami-Farahani… - Research on Chemical …, 2016 - Springer
Research on Chemical Intermediates, 2016Springer
Pechmann condensation reaction of 3-hydroxyphenol and ethyl acetoacetate in the
presence of 1, 1′‐butylenebispyridinium hydrogen sulfate as an efficient, green, and
recyclable catalyst produces 7-hydroxy-4-methylcoumarin in good yield under solvent-free
conditions at room temperature. This catalyst has advantages such as the following: good to
excellent yields, short reaction times, simplicity in operation, and easy workup procedure.
Abstract
Pechmann condensation reaction of 3-hydroxyphenol and ethyl acetoacetate in the presence of 1,1′‐butylenebispyridinium hydrogen sulfate as an efficient, green, and recyclable catalyst produces 7-hydroxy-4-methylcoumarin in good yield under solvent-free conditions at room temperature. This catalyst has advantages such as the following: good to excellent yields, short reaction times, simplicity in operation, and easy workup procedure.
Springer
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