Background and Purpose—A primary goal of acute ischemic stroke (AIS) management is to
maximize perfusion in the affected region and surrounding ischemic penumbra. However,
interventions to maximize perfusion, such as flat head-of-bed (HOB) positioning, are
currently prescribed empirically. Bedside monitoring of cerebral blood flow (CBF) allows the
effects of interventions such as flat HOB to be monitored and may ultimately be used to
guide clinical management. Methods—Cerebral perfusion was measured during HOB …

OBJECTIVE: The current study sought to demonstrate that diffuse correlation spectroscopy
(DCS) is sensitive to changes in cerebral blood flow (CBF) with head of bed (HOB)
manipulation in acute stroke patients and to correlate blood flow changes with transcranial
Doppler and clinical data. BACKGROUND: A primary goal of acute ischemic stroke
management is to maximize perfusion in the affected region and surrounding ischemic
penumbra. However, interventions to maximize perfusion such as flat HOB positioning are …