… of the experiment. Central composite design was used for method optimization. The
investigated response is resolution and capacity factors for each macrolide antibiotics. Acetonitrile (…

… The aim of this study was to optimize the solid-phase extraction method of several antibiotics
… of the device, step followed by applying the experimental conditions previously established. …

… The mobile phase was buffered at pH 7.0 to optimise detector sensitivity. However, since
only a small … 4) and the experimental macrolide, LY281389, in dog plasma using a liquid–liquid …

… compounds including tetracyclines, sulfonamides, macrolides and quinolones. LC–MS/MS …
selection of experimental conditions. For that purpose it was crucial to optimize a number of …

… Our preliminary experiments on the absolute recoveries of internal standards using 100 mL
… For example, erythromycin- 13 C 2 was used as an internal standard for all macrolides in …

… Spiramycin (SPY) is a macrolide antibacterial that is used similarly to erythromycin in the …
method to minor changes in the optimized experimental conditions was demonstrated. None of …

… of the experiment. Central composite design was used for method optimization. The
investigated response is resolution and capacity factors for each macrolide antibiotics. Acetonitrile (…

… important classes of antibiotics (of the macrolide, sulfonamide… one set of HF-LPME conditions,
followed by determination by … obtained under these optimized experimental conditions at a …

… For the analysis of macrolides, many experiments were performed using MeCN or MeOH as
… was optimized to determine 20 compounds including 16 parent macrolide antibiotics and 4 …

… experimental conditions were optimized including delay, which is an important parameter of
quantification. Three kinds of macrolide antibiotics … obtained by the high performance liquid …