The superior colliculus (SC) receives diverse and robust cortical inputs to drive a range of
cognitive and sensorimotor behaviors. However, it remains unclear how descending cortical
input arising from higher-order associative areas coordinate with SC sensorimotor networks
to influence its outputs. Here, we construct a comprehensive map of all cortico-tectal
projections and identify four collicular zones with differential cortical inputs: medial (SC. m),
centromedial (SC. cm), centrolateral (SC. cl) and lateral (SC. l). Further, we delineate the …