Osteoarthritis (OA) is a major cause of pain and disability in the aging population, but its
pathogenesis remains incompletely understood. Alterations beneath the articular cartilage at
the osteochondral junction are attracting interest as possible mediators of pain and structural
progression in OA. Osteochondral changes occur early during the development of OA and
may aggravate pathology elsewhere in the joint. Loss of osteochondral integrity removes the
barrier between intra-articular and subchondral compartments, exposing subchondral bone …

Osteochondral alterations in osteoarthritis | ECTS2014 | European Calcified Tissue Society
Congress 2014 | Bone Abstracts … Osteochondral alterations in osteoarthritis …
Osteochondral alterations in osteoarthritis …