This pragmatic mix-method study, using the case of one rural community and its District, investigates the impact of out-migration on the socio-economic development of rural Ghana. To analyze the prospect of an integrated approach to rural development. The study revealed that the current development and educational models in Ghana are fueling high rural outmigration. This in turn has created a development challenge of ‘double jeopardy of rurality’. A situation where rural areas are experiencing slow socio-economic development. In addition to indirectly paying for the cost of the negative effect of rural-urban migration. This is evidenced by skewed resources allocation in favour of urban areas to combat the problems of overcrowding cities. The study argues for a double-edged approach that weave together relevant education, innovative agriculture livelihoods, and effective decentralisation into an integrated whole. This approach has the prospect of transforming rural communities in Ghana from the current state of being the source region of socio-economic deficit to sites of rich capital accumulation and generative socio-cultural processes to drive national development