Outbreak of beriberi in the state of Maranhão, Brazil: revisiting the mycotoxin aetiologic hypothesis

HCAV Lima, EAS Porto, JRP Marins… - Tropical …, 2010 - journals.sagepub.com
HCAV Lima, EAS Porto, JRP Marins, RM Alves, RR Machado, KNL Braga, FB de Paiva…
Tropical doctor, 2010journals.sagepub.com
Beriberi is caused by thiamine deficiency. Early 20th century epidemics in Japan were
attributed to rice contaminated by citreoviridin mycotoxin. Our investigation of an outbreak of
beriberi in Brazil showed an association of beriberi with the consumption of poor quality
subsistence farming rice, although, unlike other investigators of this outbreak, we did not
identify citreoviridin producing fungi in the implicated rice.
Beriberi is caused by thiamine deficiency. Early 20th century epidemics in Japan were attributed to rice contaminated by citreoviridin mycotoxin. Our investigation of an outbreak of beriberi in Brazil showed an association of beriberi with the consumption of poor quality subsistence farming rice, although, unlike other investigators of this outbreak, we did not identify citreoviridin producing fungi in the implicated rice.
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