Outer membrane vesicles as a candidate vaccine against edwardsiellosis
SB Park, HB Jang, SW Nho, IS Cha, J Hikima… - PloS one, 2011 - journals.plos.org
Infection with Edwardsiella tarda, a Gram-negative bacterium, causes high morbidity and
mortality in both marine and freshwater fish. Outer membrane vesicles (OMVs) released from
Gram-negative bacteria are known to play important roles in bacterial pathogenesis and
host immune responses, but no such roles for E. tarda OMVs have yet been described. In the
present study, we investigated the proteomic composition of OMVs and the
immunostimulatory effect of OMVs in a natural host, as well as the efficacy of OMVs when …
mortality in both marine and freshwater fish. Outer membrane vesicles (OMVs) released from
Gram-negative bacteria are known to play important roles in bacterial pathogenesis and
host immune responses, but no such roles for E. tarda OMVs have yet been described. In the
present study, we investigated the proteomic composition of OMVs and the
immunostimulatory effect of OMVs in a natural host, as well as the efficacy of OMVs when …
Outer membrane vesicles as a candidate vaccine against edwardsiellosis.
PSB Park SeongBin, JHB Jang HoBin… - 2011 - cabidigitallibrary.org
Infection with Edwardsiella tarda, a Gram-negative bacterium, causes high morbidity and
mortality in both marine and freshwater fish. Outer membrane vesicles (OMVs) released from
Gram-negative bacteria are known to play important roles in bacterial pathogenesis and
host immune responses, but no such roles for E. tarda OMVs have yet been described. In the
present study, we investigated the proteomic composition of OMVs and the
immunostimulatory effect of OMVs in a natural host, as well as the efficacy of OMVs when …
mortality in both marine and freshwater fish. Outer membrane vesicles (OMVs) released from
Gram-negative bacteria are known to play important roles in bacterial pathogenesis and
host immune responses, but no such roles for E. tarda OMVs have yet been described. In the
present study, we investigated the proteomic composition of OMVs and the
immunostimulatory effect of OMVs in a natural host, as well as the efficacy of OMVs when …
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