Overcoming barriers in cystic fibrosis therapy through inhalational lipid nanoparticles: Challenges and advances

MM Anjum, KK Patel, S Bhattacharya, DK Arya… - Journal of Drug Delivery …, 2023 - Elsevier
Cystic fibrosis (CF) is a genetic disorder that follows an autosomal recessive pattern of
inheritance and is characterized by mutations in the cystic fibrosis transmembrane
conductance regulator (CFTR) gene. Cystic fibrosis is implicated in the inflammatory
cascades and is recognized as a systemic disease that extends beyond pulmonary
involvement, impacting various essential organs and resulting in a plethora of comorbidities.
Cystic fibrosis broadly impacts pulmonary airway that is associated with both mortality and …
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