Oxaliplatin induced-neuropathy in digestive tumors

M Sereno, G Gutiérrez-Gutiérrez… - Critical reviews in …, 2014 - Elsevier
M Sereno, G Gutiérrez-Gutiérrez, C Gómez-Raposo, M López-Gómez, M Merino-Salvador…
Critical reviews in oncology/hematology, 2014Elsevier
Oxaliplatin is one of the main drugs used in digestive tumors treatment. Peripheral
neuropathy is a well-recognized dose-limiting toxicity of OXL. Two types of neuropathy have
been described with this agent: acute or transient and chronic or persistent, with different
etiology, clinical manifestations and prognosis. This paper is an exhaustive review about the
main aspects of oxaliplatin induced peripheral neuropathy, focus in clinical features,
treatment, prevention strategies and future approach.
Abstract
Oxaliplatin is one of the main drugs used in digestive tumors treatment. Peripheral neuropathy is a well-recognized dose-limiting toxicity of OXL. Two types of neuropathy have been described with this agent: acute or transient and chronic or persistent, with different etiology, clinical manifestations and prognosis.
This paper is an exhaustive review about the main aspects of oxaliplatin induced peripheral neuropathy, focus in clinical features, treatment, prevention strategies and future approach.
Elsevier
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