P0174-Mindfulness-based cognitive therapy reduces depression symptoms in people with a traumatic brain injury: Results from a pilot study

M Bedard, M Felteau, S Marshall, S Dubois… - European …, 2008 - cambridge.org
M Bedard, M Felteau, S Marshall, S Dubois, B Weaver, C Gibbons, K Morris, S Ross…
European Psychiatry, 2008cambridge.org
Background and Aims: Major depression is a significant problem for people with a traumatic
brain injury (TBI) and its treatment remains difficult. A promising approach to treat
depression is Mindfulness-based cognitive therapy (MBCT), a relatively new therapeutic
approach rooted in mindfulness based stress-reduction (MBSR) and cognitive behavioral
therapy (CBT). We conducted this study to examine the effectiveness of MBCT in reducing
depression symptoms among people who have a TBI. Methods: Twenty individuals …
Background and Aims
Major depression is a significant problem for people with a traumatic brain injury (TBI) and its treatment remains difficult. A promising approach to treat depression is Mindfulness-based cognitive therapy (MBCT), a relatively new therapeutic approach rooted in mindfulness based stress-reduction (MBSR) and cognitive behavioral therapy (CBT). We conducted this study to examine the effectiveness of MBCT in reducing depression symptoms among people who have a TBI.
Methods
Twenty individuals diagnosed with major depression were recruited from a rehabilitation clinic and completed the 8-week MBCT intervention. Instruments used to measure depression symptoms included: BDI-II, PHQ-9, HADS, SF-36 (Mental Health subscale), and SCL-90 (Depression subscale). They were completed at baseline and post-intervention.
Results
All instruments indicated a statistically significant reduction in depression symptoms post-intervention (p < .05). For example, the total mean score on the BDI-II decreased from 25.2 (9.8) at baseline to 18.2 (11.7) post-intervention (p=.001). Using a PHQ threshold of 10, the proportion of participants with a diagnosis of major depression was reduced by 59% at follow-up (p=.012).
Conclusions
Most participants reported reductions in depression symptoms after the intervention such that many would not meet the criteria for a diagnosis of major depression. This intervention may provide an opportunity to address a debilitating aspect of TBI and could be implemented concurrently with more traditional forms of treatment, possibly enhancing their success. The next step will involve the execution of multi-site, randomized controlled trials to fully demonstrate the value of the intervention.
Cambridge University Press