PLGA nanoparticle preparations by emulsification and nanoprecipitation techniques: Effects of formulation parameters

KY Hernández-Giottonini, RJ Rodríguez-Córdova… - Rsc Advances, 2020 - pubs.rsc.org
This study presents the influence of the primary formulation parameters on the formation of
poly-DL-lactic-co-glycolic nanoparticles by the emulsification-solvent evaporation, and the
nanoprecipitation techniques. In the emulsification-solvent evaporation technique, the
polymer and tensoactive concentrations, the organic solvent fraction, and the sonication
amplitude effects were analyzed. Similarly, in the nanoprecipitation technique the polymer
and tensoactive concentrations, the organic solvent fraction and the injection speed were …

[引用][C] PLGA nanoparticle preparations by emulsification and nanoprecipitation techniques: effects of formulation parameters, RSC Adv. 10 (2020) 4218–4231

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