PLOD2 in cancer research

H Du, M Pang, X Hou, S Yuan, L Sun - Biomedicine & Pharmacotherapy, 2017 - Elsevier
… Thus far, there have been no reviews on PLOD2 in cancer research. In this article, we will …
of PLOD2 in different cancers and explore the potential pharmacologic inhibitors of PLOD2 for …

Proteomics profiling of colorectal cancer progression identifies PLOD2 as a potential therapeutic target

Y Shao, K Xu, X Zheng, B Zhou, X Zhang… - Cancer …, 2022 - Wiley Online Library
… Remarkably, we found that higher PLOD2 expression was associated with poorer overall …
the PLOD2 expression in six CRC cell lines and chose the two with the highest PLOD2

PLOD2 contributes to drug resistance in laryngeal cancer by promoting cancer stem cell-like characteristics

X Sheng, Y Li, Y Li, W Liu, Z Lu, J Zhan, M Xu, L Chen… - BMC cancer, 2019 - Springer
… in laryngeal cancer cells, we found that PLOD2 overexpression … research on correlations
between PLOD2 and CSCs. In 1996, PLOD2 was first reported in breast cancer research

PLOD2 high expression associates with immune infiltration and facilitates cancer progression in osteosarcoma

Z Wang, G Fan, H Zhu, L Yu, D She, Y Wei… - Frontiers in …, 2022 - frontiersin.org
… In our research, we found that PLOD2 was highly expressed in OS. Through functional
experiments we found that PLOD2 … the expression of PLOD2 in different cancer types with TIMER …

Targeting PLOD2 suppresses invasion and metastatic potential in radiorecurrent prostate cancer

G Frame, H Leong, R Haas, X Huang, J Wright… - BJC reports, 2024 - nature.com
PLOD2 is a negative prognostic factor associated with biochemical relapse, … cancer.
Mechanistically, HIF1α upregulation drives PLOD2 expression in our radiorecurrent prostate cancer

Pan-cancer analyses reveal oncogenic and immunological role of PLOD2

Q Xu, N Kong, Y Zhao, Q Wu, X Wang, X Xun… - Frontiers in …, 2022 - frontiersin.org
… showed that the PLOD2 expression in gastric cancer was significantly higher than normal
tissues. In order to investigate the research status of PLOD2 and gastric cancer, we conducted …

PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC

H Du, Y Chen, X Hou, Y Huang, X Wei, X Yu… - Cell death & …, 2017 - nature.com
… , the regulatory mechanism and function of PLOD2 in human lung adenocarcinoma is …
cancers, especially in non-small-cell lung cancer (NSCLC). In this study, we found that PLOD2

PLOD2 is a potent prognostic marker and associates with immune infiltration in cervical cancer

G Li, X Wang, G Liu - BioMed Research International, 2021 - Wiley Online Library
… ; and the correlations between PLOD2 and cancer immune infiltrates were … PLOD2 was
increased in various cancers, and meta-analysis in the Oncomine database revealed that PLOD2

PLOD2 as a potential regulator of peritoneal dissemination in gastric cancer

Y Kiyozumi, M Iwatsuki, J Kurashige… - … journal of cancer, 2018 - Wiley Online Library
… We analyzed PLOD2 expression levels in PLOD2 low HSC58 cells after exposure to 21%
or 0.5% O 2 for 48 hr, to determine that hypoxia can influence GC cell phenotype under …

The collagen-modifying enzyme PLOD2 is induced and required during L1-mediated colon cancer progression

S Cheriyamundath, A Kumar, N Gavert… - International journal of …, 2021 - mdpi.com
… The PLOD2-mediated changes in collagen organization are believed to play a key role in …
of a wide variety of cancer cells [15]. In this study, we investigated the roles of PLOD2 in the L1-…