PRAME gene expression in childhood acute lymphoblastic leukemia: impact on prognosis.
CA Abdelmalak, RS Yahya, DM Elghannam… - Clinical …, 2014 - europepmc.org
Background The PRAME (preferentially expressed antigen of melanoma) gene is frequently
overexpressed in a wide variety of malignant diseases, including acute myeloid leukemia
(AML) and acute B-cell malignancies. Aim To study the expression of PRAME gene and
clarify its prognostic impact on disease outcome. Methods Screening for PRAME gene
expression was assessed using real-time reverse transcriptase polymerase chain reaction
in 55 pretreated ALL bone marrow samples. Results PRAME positivity was found in 14 …
overexpressed in a wide variety of malignant diseases, including acute myeloid leukemia
(AML) and acute B-cell malignancies. Aim To study the expression of PRAME gene and
clarify its prognostic impact on disease outcome. Methods Screening for PRAME gene
expression was assessed using real-time reverse transcriptase polymerase chain reaction
in 55 pretreated ALL bone marrow samples. Results PRAME positivity was found in 14 …
[PDF][PDF] PRAME gene expression in childhood acute lymphoblastic leukemia: impact on prognosis
A Ca, Y Rs, EK Ae, HM Abd El Messih - Clin Lab, 2014 - researchgate.net
Background: The PRAME (preferentially expressed antigen of melanoma) gene is frequently
overexpressed in a wide variety of malignant diseases, including acute myeloid leukemia
(AML) and acute B-cell malignancies. Aim: To study the expression of PRAME gene and
clarify its prognostic impact on disease outcome. Methods: Screening for PRAME gene
expression was assessed using real-time reverse transcriptase polymerase chain reaction
in 55 pretreated ALL bone marrow samples. Results: PRAME positivity was found in 14 …
overexpressed in a wide variety of malignant diseases, including acute myeloid leukemia
(AML) and acute B-cell malignancies. Aim: To study the expression of PRAME gene and
clarify its prognostic impact on disease outcome. Methods: Screening for PRAME gene
expression was assessed using real-time reverse transcriptase polymerase chain reaction
in 55 pretreated ALL bone marrow samples. Results: PRAME positivity was found in 14 …
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