WGCNA: an R package for weighted correlation network analysis

P Langfelder, S Horvath - BMC bioinformatics, 2008 - Springer
WGCNA has been used to analyze gene expression … R package that summarizes and
standardizes methods and functions. To address this need, we introduce the WGCNA R package

Identification of susceptibility modules and genes for cardiovascular disease in diabetic patients using WGCNA analysis

W Liang, F Sun, Y Zhao, L Shan… - Journal of diabetes …, 2020 - Wiley Online Library
… We used the WGCNA R package to construct the coexpression network [8]. First, samples
were clustered to assess the presence of any obvious outliers. Second, the automatic network …

Identification of gene modules and hub genes in colon adenocarcinoma associated with pathological stage based on WGCNA analysis

H Wang, J Liu, J Li, D Zang, X Wang, Y Chen, T Gu… - Cancer Genetics, 2020 - Elsevier
… TCGA database for WGCNA analysis. After the processing of edgeR package based on R
Studio, we found there were a total of 2853 differentially expressed genes (DEGs) for further …

[HTML][HTML] Identification of key modules and genes associated with breast cancer prognosis using WGCNA and ceRNA network analysis

X Yin, P Wang, T Yang, G Li, X Teng, W Huang… - Aging (albany …, 2021 - ncbi.nlm.nih.gov
… A total of 3301 differential genes were identified between the tumor and normal samples
using the DESeq2 R package, at thresholds of |log2FC| > 2 and adj-p < 1e-3. Differentially …

Identification of key gene modules in human osteosarcoma by co‐expression analysis weighted gene co‐expression network analysis (WGCNA)

X Liu, AX Hu, JL Zhao, FL Chen - Journal of cellular …, 2017 - Wiley Online Library
… the function softConnectivity from package WGCNA, with the “… the pickSoftThreshold function
of WGCNA. This function provides … implemented in the R package WGCNA. Cluster analysis …

Co-expression modules construction by WGCNA and identify potential prognostic markers of uveal melanoma

Q Wan, J Tang, Y Han, D Wang - Experimental eye research, 2018 - Elsevier
… melanoma were used to construct the co-expression module by WGCNA package tool. The
flashClust tools package was used to perform the cluster analysis on these samples and the …

WGCNA application to proteomic and metabolomic data analysis

G Pei, L Chen, W Zhang - Methods in enzymology, 2017 - Elsevier
… , an R analytical package named as weighted gene coexpression network analysis (WGCNA)
was … for applying the WGCNA approach in analyzing proteomic and metabolomic datasets. …

Identification of important modules and biomarkers in breast cancer based on WGCNA

Z Tian, W He, J Tang, X Liao, Q Yang… - OncoTargets and …, 2020 - Taylor & Francis
… Firstly, we evaluated the 3137 variant genes to test their availability and used the R package
termed “WGCNA” to construct a gene co-expression network. Subsequently, we constructed …

Identification of key pathways and genes in the dynamic progression of HCC based on WGCNA

L Yin, Z Cai, B Zhu, C Xu - Genes, 2018 - mdpi.com
… From thousands of genes, the interesting gene modules can be identified by WGCNA, and
then, the … WGCNA is a freely accessible R package for the construction of weighted gene co-…

Integrated analysis of WGCNA and machine learning identified diagnostic biomarkers in dilated cardiomyopathy with heart failure

Y Zhu, X Yang, Y Zu - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
… We used the weighted gene co-expression network analysis (WGCNApackage “pROC”.
Additionally, we visualized Pearson’s correlation among the 13 feature genes by the R package