Pain associated with treatment of Dupuytren contracture with collagenase clostridium histolyticum

R Sanjuan-Cerveró, FJ Carrera-Hueso… - The Journal of Hand …, 2017 - Elsevier
Purpose The primary objective of this study was to quantify the degree of pain associated
with collagenase Clostridium histolyticum (CCH) injection and to determine whether it is
related to other factors in the intervention. Methods A prospective study of 135 patients was
performed to evaluate pain at 3 points during treatment:(1) after CCH injection, using a
numerical rating scale (NRS),(2) a binary (positive/negative) assessment before
manipulation 24 hours after CCH and after removing the bandage, and (3) after joint …
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