with collagenase Clostridium histolyticum (CCH) injection and to determine whether it is
related to other factors in the intervention. Methods A prospective study of 135 patients was
performed to evaluate pain at 3 points during treatment:(1) after CCH injection, using a
numerical rating scale (NRS),(2) a binary (positive/negative) assessment before
manipulation 24 hours after CCH and after removing the bandage, and (3) after joint …