… Derivation of patient-derived xenograft models of human breast cancer in mice. Tumor
slices are implanted into the cleared inguinal fat pad of mice (MFP) concurrently with a …

… , patient-derived xenograft (PDX) models of many types of tumors including breast cancer
have emerged as a powerful tool for predicting drug efficacy and for understanding tumor …

… and differential treatment response, the lethal aspects of breast cancer, in order to “personalize”
effective treatment. Patient-derived xenograft (PDX) models hold high promise as a …

… breast cancer patient-derived xenografts (BM-PDXs) from ER + , HER2 + , and TN subtypes
and a matching TN cell line, which retain tumor … fashion to breast cancer brain metastasis. …

… and classification of patient-derived human breast tumor xenograft models that have the …
cancer therapy based on the unique driver signaling pathways in breast tumor subtypes. …

… metastasis profiles and throughout successive xenograft generations. A, aCGH … breast tumor
(upper), breast tumor-derived xenograft (middle), and axillary metastasis-derived xenograft (…

… Patient-derived xenografts (PDXs) are increasingly used as a … molecular characterization
of breast cancer along with the … clinical study (the Breast Cancer Genome Guided Therapy …

… of patient-derived xenograft (PDX) models of human cancers … in mice has been particularly
effective for breast cancer [1,2,3,… attempt growth of a variety of cancers, including breast [13]. …

… Here we describe six breast cancer cell lines derived from patient-derived xenografts (PDX)
and their general … Existing human breast cancer cell lines, patient-derived xenografts (PDX), …

… Patient-derived tumour xenograft (PDTX) models prevail as arguably the most powerful in …
they capture cancer’s heterogeneous nature. Herein, we review current breast cancer models …